Tuesday, 02 April 2019

8.50

Session 5: Computational Protein Modelling
Invited Speaker: Michele Vendruscolo, University of Cambridge

Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins

Short Lectures:

Sowmya Indrakumar/ Günther Peters - Technical University of Denmark
Computational predictions to aid formulation of biologics

Marco Polimeni/ Mikael Lund - Lund University
Combining models and experiments for protein-protein interactions in solutions

Andreas Tosstorff / Gerhard Winter - Ludwig-Maximilians-Universität München
Exploring chemical space for new excipients to stabilize therapeutic proteins

Miko Schleinitz - Technische Universität Dortmund
Prediction of protein-protein interactions using ePC-SAFT

10.40 Coffee Break, Posters Are Up
11.00

Session 6: Protein Interactions
Invited Speaker: Per Olof Wahlund - Novo Nordisk

Asymmetrical Flow-Field Flow Fractionation as tool for assessing protein interaction

Short Lectures:

Marcello Morales/ Chris van de Walle – Astra Zeneca
Cucurbit[7]uril aids in stabilizing an aggregation-prone monoclonal antibody

Aisling Roche/ Robin Curtis - University of Manchester
Using Rheology as an Analytical Tool in Biopharmaceutical Development

Christin Pohl / Allan Nørgaard – Novozymes
Biophysical Formulation Studies on an Anti-Microbial Peptide - The Role of Point Mutations in Protein

Ruben Wälchli – ETH Zurich
Native protein-protein interactions and long-term aggregation rates of antibody solutions

12.50 Lunch Break, Posters Are Up
Exhibitors lunch talks

14.00-14.10 Fluidic

14.10-14.20 Xtal Concepts

14.30

Session 7: New Frontiers
Invited Speaker: Paolo Arosio, ETH Zürich

Microfluidic technology and liquid-liquid phase separation for the analysis and development of protein formulations

Short Lectures:

Stefan Hervo Hansen / Mikael Lund, Lund University
In Silico Model for Salting-in and Salting-out: From Caffeine to Proteins

Sarah Hedberg – Imperial College
Stability mapping of antibody therapeutics using protein-protein interactions

Eugenia Hoffmann – Roche Diagnostics GmbH
Advanced bioanalysis of immune complexes for a better understanding of immunogenicity

16.00 Closing remarks - End of conference

Order of sessions can be changed.